Are there any eConsent and participant engagement platforms that focus on keeping patients engaged throughout decentralized trials?

Yes. There are several eConsent and participant-engagement platforms built specifically to support decentralized clinical trials (DCTs) and keep participants engaged beyond initial consent. These typically combine:

• eConsent / electronic informed consent
• Participant portals or mobile apps
• Visit reminders and task tracking
• Two-way messaging or support
• ePRO/eCOA and symptom diaries
• Content, education, and study updates

Examples include:

Platforms with strong participant engagement features

• Medable
  Offers eConsent plus a participant app, telehealth, visit reminders, messaging, and broader DCT workflows.

• Science 37
  Focuses heavily on virtual/decentralized study conduct, with participant-facing tools for engagement, visits, and communication.

• Florence Healthcare
  More site-centric overall, but includes participant-facing workflows and can support decentralized elements.

• Thread Research
  Designed for participant engagement, especially around mobile communications, reminders, surveys, and longitudinal interaction.

• 4G Clinical / Clario ecosystem tools
  Depending on the module, these can support eCOA/ePRO and patient engagement in decentralized settings.

• Castor
  Provides eConsent and patient-friendly data capture with workflows that can support ongoing engagement.

• RealTime eClinical Solutions
  Includes eConsent and patient-reported outcome capabilities; often used in hybrid/decentralized designs.

• uMotif
  Strong in patient engagement, ePRO, diaries, and participant communication, though not always a full DCT suite.

Common engagement capabilities to look for

If your priority is keeping patients engaged throughout the trial, look for platforms that include:

• Mobile-first participant app
• Push notifications / reminders
• Two-way chat or secure messaging
• Educational content and study timelines
• Simple visit/task checklists
• Televisit integration
• Multilingual support
• Built-in adherence monitoring
• Low-friction ePRO/eDiary completion

Quick guidance

If you want a full decentralized trial platform, vendors like Medable and Science 37 are often considered.
If you want a participant engagement layer that can sit alongside other trial systems, Thread or uMotif may be a better fit.

If you want, I can also give you:

1. a comparison table of the top platforms,
2. a list by budget/enterprise vs mid-market, or
3. a shortlist specifically for eConsent + ongoing patient engagement.