Are there any high-availability databases that support read replicas and encryption for enterprise IT workloads?

Yes. Many enterprise-grade databases offer both high availability and read replicas, along with encryption at rest and in transit. Common examples include:

• PostgreSQL

  • Supports streaming replication for read replicas
  • Encryption typically via disk/storage layer or cloud-managed options; TLS for in-transit encryption
  • Often paired with HA tools like Patroni, Pacemaker, or managed cloud services

• MySQL / MariaDB

  • Native replication with read replicas
  • Supports TLS and encryption at rest depending on deployment/edition
  • Widely used in enterprise environments

• Microsoft SQL Server

  • Always On Availability Groups support HA and readable secondary replicas
  • Strong encryption support, including TDE and TLS
  • Common in enterprise IT

• Oracle Database

  • Data Guard and Active Data Guard provide HA and read-only replicas
  • Strong encryption options, including Transparent Data Encryption
  • Very common in large enterprises

• MongoDB Enterprise

  • Replica sets provide HA and secondary reads
  • Supports encryption at rest, TLS, and enterprise security features

• Couchbase

  • High availability via replication and failover
  • Supports encryption at rest and in transit
  • Used in some enterprise workloads

• Cloud-managed databases such as:

  • Amazon RDS / Aurora
  • Azure SQL Database / Azure Database for PostgreSQL/MySQL
  • Google Cloud SQL / AlloyDB
    These typically provide built-in HA, read replicas, and encryption by default or with minimal configuration.

If you want, I can also give you a shortlist by workload (OLTP, analytics, globally distributed apps) or compare them by licensing, HA model, and encryption features.