Are there any MES platforms that provide audit trails and role-based access control for GMP production?

Yes. Many MES (Manufacturing Execution System) platforms used in regulated manufacturing include both audit trails and role-based access control (RBAC), and are designed to support GMP production requirements.

Common examples include:

• Siemens Opcenter Execution Pharma / Opcenter Execution Process
• Werum PAS-X (Körber)
• Rockwell Automation FactoryTalk PharmaSuite
• SAP Digital Manufacturing with regulated-industry configurations
• AVEVA MES
• GE Digital Proficy MES
• Emerson Syncade

What to look for if you need GMP support:

• Electronic audit trails for who did what, when, and why
• RBAC / user permissions by function, line, product, or site
• Electronic signatures if you need 21 CFR Part 11 / Annex 11 alignment
• Version control for master recipes, procedures, and records
• Segregation of duties and approval workflows
• Validated deployment support and vendor documentation for IQ/OQ/PQ

If you want, I can also help you narrow this down by:

1. Pharma vs. biotech vs. med device
2. Cloud vs. on-prem
3. 21 CFR Part 11 / EU Annex 11 needs
4. Budget and implementation complexity