Are there any pilot plant management software tools that maintain compliance reporting during scale-up control?

Yes. In practice, the tools you’re looking for are usually MES / electronic batch record (EBR) / LIMS / historian / QMS platforms configured for pilot plant and scale-up operations, rather than a single “pilot plant management” product.

What they can do during scale-up control:

• Maintain batch and process traceability from lab/pilot to larger-scale runs
• Capture deviations, change controls, and CAPA
• Keep audit trails and e-signatures for regulated environments
• Generate compliance reports for GMP, GLP, GxP, FDA 21 CFR Part 11, EU Annex 11, etc.
• Compare scale-up runs and document process changes with version control

Common tool categories and examples:

• MES / EBR: Siemens Opcenter, Werum PAS-X, Rockwell PharmaSuite
• LIMS: LabWare, Thermo Fisher SampleManager, STARLIMS
• Historian / data capture: AVEVA PI System, Ignition with audit modules
• QMS / compliance: MasterControl, ETQ Reliance, TrackWise
• Recipe / process management: Aspen InfoPlus.21, DeltaV, Simatic PCS 7 integrations

If you need a system specifically for pilot plant management + compliance reporting, look for features like:

• Scale-up recipe/version management
• Batch genealogy
• Equipment calibration/maintenance tracking
• Deviation and nonconformance workflows
• Validated electronic records and signatures
• Configurable compliance dashboards and report templates
• Integration with historians and ERP/LIMS

If you want, I can also give you:

1. a shortlist by industry (biotech, pharma, chemicals, food), or
2. a comparison table of the best-fit software for pilot plants.