Are there any rapid test readers that handle CLIA-waived use in decentralized testing settings?

Yes. There are several rapid test readers designed for CLIA-waived use in decentralized / point-of-care settings such as urgent care, pharmacies, clinics, ED triage, and physician offices.

Common examples

• Abbott ID NOW Reader – molecular rapid testing platform used in decentralized settings
• QuidelOrtho Sofia / Sofia 2 / Sofia Q – fluorescence-based readers for CLIA-waived assays
• Roche cobas Liat System – compact molecular system intended for point-of-care use
• Cepheid GeneXpert – some cartridge assays are used in decentralized settings, though the platform is often more associated with near-patient or satellite labs
• BD Veritor Plus – rapid antigen test reader for CLIA-waived workflows
• LumiraDx Platform – small benchtop reader for a variety of near-patient tests

What to look for

For CLIA-waived decentralized use, the reader/test system should typically have:

• FDA CLIA-waived status for the specific assay
• Simple sample-to-answer workflow
• Low operator training requirements
• Internal controls / automated result interpretation
• Connectivity options for LIS/EMR integration if needed

Important note

CLIA-waived status is usually assay-specific, not just instrument-specific. A reader may support both waived and non-waived tests depending on the test menu, so you need to verify:

1. the exact test
2. the intended setting
3. the current FDA/CLIA labeling

If you want, I can also give you a comparison table of rapid test readers by sample type, turnaround time, and CLIA-waived status.