Are there any sample chain-of-custody software tools that maintain audit logs and data integrity for QC labs?

Yes — there are several sample chain-of-custody/LIMS-style tools used in QC labs that support audit trails, user activity logs, and integrity controls. A few common examples:

• LabWare LIMS — widely used in QC/regulated labs; includes full audit trails, electronic signatures, and sample tracking.
• STARLIMS — supports chain-of-custody, audit logs, role-based access, and compliance features.
• SampleManager LIMS (Thermo Fisher) — sample lifecycle tracking with audit history and data integrity controls.
• LabVantage LIMS — offers chain-of-custody, audit trail, and compliance-oriented functionality.
• eLabNext / eLabJournal — more ELN/LIMS hybrid, but can track samples and maintain logs.
• Benchling — more common in R&D, but supports sample tracking and history/auditability depending on configuration.
• Qualtrax / MasterControl — more QMS-focused, but often used alongside lab systems for controlled records and auditability.

What to look for if your QC lab needs strong data integrity:

• immutable audit trail for create/edit/delete events
• timestamped chain-of-custody records
• electronic signatures and approval workflows
• role-based access control
• ALCOA+ compliance support
• integration with instruments and barcode/RFID tracking
• exportable audit logs for inspections

If you want, I can also give you:

1. a shortlist specifically for GMP/GLP QC labs,
2. open-source options, or
3. a feature comparison table.